Thinking through Errance: Journeying and Waiting among African Travelers in Quito and Dakar

RESUMEN: A partir del cambio de milenio, Ecuador se ha convertido en un lugar de paso, pero también de residencia para migrantes de diferentes países del mundo. Mientras que la fuerza de atracción de este país proviene de requisitos migratorios flexibles como resultado de una política de ciudadanía universal, las condiciones económicas no estimulan la posibilidad de quedarse. Este artículo tiene como punto de partida una reflexión previa sobre el concepto errancia que surgió de un acercamiento a las historias de africanos que esperaban en Dakar (Senegal) para continuar el viaje fuera de su continente. Contrastamos esta experiencia con la de otros africanos que han atravesado el Atlántico y han llegado a Quito. Dos opciones se presentan a estos últimos: continuar el viaje hacia Estados Unidos o quedarse. En ambos casos, las políticas migratorias, el valor de los papeles (pasaportes y visas) y las formas de socialidad influyen en su experiencia como viajeros. En el caso de quienes continúan el viaje hacia Estados Unidos,los riesgos de la travesía se convierten en pruebas de aptitud para recibir asilo.ABSTRACT: Since the beginning of the 21st century, Ecuador has been a point of transit but also of residence for migrants from around the world. While the attraction of this country resides in the flexible regulations of migration which stem from its policy of universal citizenship, the economic conditions there do not encourage migrants to stay. The starting point of this article is a previous study of the concept of errance which emerged from listening to the stories of Africans who were waiting in Dakar, Senegal, as they sought a way to leave from the continent from Africa. The article contrasts their experiences with those of other Africans who manage to cross the Atlantic and land in Quito. There are two options available for them: to either continue the journey toward the United States or remain in Ecuador. In both cases, migration policies, immigration papers and socialities are factors which shape their experience as travelers. For those who continue on their journey to the United States, the risks they run become a proof of their worthiness to be granted asylum

CXCL12 expression by healthy and malignant ovarian epithelial cells

<p>Abstract</p> <p>Background</p> <p>CXCL12 has been widely reported to play a biologically relevant role in tumor growth and spread. In epithelial ovarian cancer (EOC), CXCL12 enhances tumor angiogenesis and contributes to the immunosuppressive network. However, its prognostic significance remains unclear. We thus compared CXCL12 status in healthy and malignant ovaries, to assess its prognostic value.</p> <p>Methods</p> <p>Immunohistochemistry was used to analyze CXCL12 expression in the reproductive tracts, including the ovaries and fallopian tubes, of healthy women, in benign and borderline epithelial tumors, and in a series of 183 tumor specimens from patients with advanced primary EOC enrolled in a multicenter prospective clinical trial of paclitaxel/carboplatin/gemcitabine-based chemotherapy (GINECO study). Univariate COX model analysis was performed to assess the prognostic value of clinical and biological variables. Kaplan-Meier methods were used to generate progression-free and overall survival curves.</p> <p>Results</p> <p>Epithelial cells from the surface of the ovary and the fallopian tubes stained positive for CXCL12, whereas the follicles within the ovary did not. Epithelial cells in benign, borderline and malignant tumors also expressed CXCL12. In EOC specimens, CXCL12 immunoreactivity was observed mostly in epithelial tumor cells. The intensity of the signal obtained ranged from strong in 86 cases (47%) to absent in 18 cases (<10%). This uneven distribution of CXCL12 did not reflect the morphological heterogeneity of EOC. CXCL12 expression levels were not correlated with any of the clinical parameters currently used to determine EOC prognosis or with HER2 status. They also had no impact on progression-free or overall survival.</p> <p>Conclusion</p> <p>Our findings highlight the previously unappreciated constitutive expression of CXCL12 on healthy epithelia of the ovary surface and fallopian tubes, indicating that EOC may originate from either of these epithelia. We reveal that CXCL12 production by malignant epithelial cells precedes tumorigenesis and we confirm in a large cohort of patients with advanced EOC that CXCL12 expression level in EOC is not a valuable prognostic factor in itself.</p> <p>Trial Registration</p> <p>ClinicalTrials.gov: <a href="http://www.clinicaltrials.gov/ct2/show/NCT00052468">NCT00052468</a></p

Year in review in Intensive Care Medicine 2009: I. Pneumonia and infections, sepsis, outcome, acute renal failure and acid base, nutrition and glycaemic control

Journal ArticleReviewSCOPUS: re.jinfo:eu-repo/semantics/publishe

Year in review in Intensive Care Medicine 2010: III. ARDS and ALI, mechanical ventilation, noninvasive ventilation, weaning, endotracheal intubation, lung ultrasound and paediatrics

SCOPUS: re.jinfo:eu-repo/semantics/publishe

Year in review in Intensive Care Medicine, 2008: II. Experimental, acute respiratory failure and ARDS, mechanical ventilation and endotracheal intubation

SCOPUS: re.jinfo:eu-repo/semantics/publishe

Year in review in Intensive Care Medicine 2010: I. Acute renal failure, outcome, risk assessment and ICU performance, sepsis, neuro intensive care and experimentals

SCOPUS: re.jinfo:eu-repo/semantics/publishe

Year in review in Intensive Care Medicine 2009: II. Neurology, cardiovascular, experimental, pharmacology and sedation, communication and teaching

N/

Soot particle formation under the competition of aggregation and surface growth

International audienc

Développement d'une cavité Multi-Spéctrale compacte pour la caractérisation embarquée d'aérosols

International audienc